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A research-informed neuromodulator approach to erectile function

Priapus Toxin®

Priapus Toxin® is a newer, research-informed option that works differently from PRP — and can complement it. A precise injection of a neuromodulator into penile tissue is used to support erectile function. Shannon holds Canadian Clinical Instructor certification for this procedure and is one of a small number of providers in Canada performing it.

Who This Helps

What men address with this procedure

Premature ejaculation
Erectile dysfunction (vascular component)
Peyronie's disease — curvature or plaque
Reduced control over ejaculatory timing
Penile tissue tension or discomfort
Wanting to enhance sexual duration and control

What It Is

How this works

A neuromodulator is injected into the penis to relax the smooth muscle within the blood vessels, supporting blood flow to the area. It's a distinct mechanism from the P-Shot®, which is why the two are often used together. This is not a standard cosmetic neuromodulator injection applied to a different location — the product, dosing, technique, injection depth, and clinical rationale are all specific to this application.

The P-Shot® 100

When Priapus Toxin® is combined with the P-Shot® in the same visit, this is Dr. Runels' P-Shot® 100 protocol — pairing regenerative PRP with a neuromodulator.

Important Safety Information

This is an off-label use of a neuromodulator, performed only by a specifically trained provider under medical delegation. As with any treatment, results vary between individuals and are not guaranteed. Full informed consent including off-label disclosure is obtained, and your suitability is confirmed at your medical assessment. Only providers listed at pshot.info are certified to perform this procedure under the Runels protocol.

The Procedure

What happens at your appointment

1

Assessment

A full health history and symptom review. Shannon will confirm candidacy and answer all questions before you commit to anything.

2

Numbing

Topical BLT 20/8/8 cream is applied and allowed to work fully. The procedure is significantly more comfortable than most men expect.

3

Injection

A neuromodulator is injected into penile tissue per the Runels Priapus Toxin® protocol. The injection itself is brief.

4

Done

No downtime. Post-procedure instructions reviewed. You leave and resume your day. Follow-up at 4–6 weeks.

What to Expect

Timeline

Procedure Time

45–60 minutes

Downtime

None

Onset

7–14 days

Duration

3–6 months at 50u · 9–12+ months at 100u

Retreatment

No sooner than 3 months

Often Combined With

P-Shot® (same appointment)

Candidacy

Good fit vs. needs discussion

Likely a good fit

  • Premature ejaculation
  • Vascular erectile dysfunction
  • Peyronie's disease
  • Penile tissue tension
  • No neuromuscular conditions

We'll need to discuss

  • Neuromuscular disease (myasthenia gravis, ALS)
  • Aminoglycoside antibiotic use
  • Botulinum toxin injection within 3 months to any site
  • Active infection at injection site
  • Pregnancy (partner — discuss implications)

Certified Provider — Verify Credentials

Verify Shannon's Priapus Toxin® certification on the official CMA provider directory.

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Part of these programs

Two or three years is long enough to wait

A free Discovery Conversation is confidential, no-pressure, and usually clarifies things fast. Most men leave knowing exactly whether this is the right direction for them.

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Flexible Payment

Money shouldn't be the reason you wait

We really do work with our patients — money should never be the reason you don't feel amazing. Most programs can be split into manageable monthly payments through Beautifi, our primary healthcare-financing partner. Checking your options is a soft credit check that won't affect your score — no obligation.

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Individual results vary and are not guaranteed. Priapus Toxin® is an off-label application of botulinum toxin type A. All procedures are performed under medical delegation from our Medical Director. Seek emergency care immediately if erection persists beyond 4 hours.
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