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A research-informed neuromodulator approach to erectile function

Priapus Toxin®

Priapus Toxin® is a newer, research-informed option that works differently from PRP — and can complement it. A precise injection of a neuromodulator into penile tissue is used to support erectile function. Shannon has years of hands-on experience performing this procedure and is an approved instructor within Dr. Charles Runels' network.

Who This Helps

What men address with this procedure

Premature ejaculation
Erectile dysfunction (vascular component)
Peyronie's disease — curvature or plaque
Reduced control over ejaculatory timing
Penile tissue tension or discomfort
Wanting to enhance sexual duration and control

What It Is

How this works

A neuromodulator is injected into the penis to relax the smooth muscle within the blood vessels, supporting blood flow to the area. It's a distinct mechanism from the P-Shot®, which is why the two are often used together. This is not a standard cosmetic neuromodulator injection applied to a different location — the product, dosing, technique, injection depth, and clinical rationale are all specific to this application.

The P-Shot® 100

When Priapus Toxin® is combined with the P-Shot® in the same visit, this is Dr. Runels' P-Shot® 100 protocol — pairing regenerative PRP with a neuromodulator.

Important Safety Information

This is an off-label use of a neuromodulator, performed only by a specifically trained provider under medical delegation. As with any treatment, results vary between individuals and are not guaranteed. Full informed consent including off-label disclosure is obtained, and your suitability is confirmed at your medical assessment. Only providers listed at pshot.info are certified to perform this procedure under the Runels protocol.

The Procedure

What happens at your appointment

1

Assessment

A full health history and symptom review. Shannon will confirm candidacy and answer all questions before you commit to anything.

2

Numbing

Topical BLT 20/8/8 cream is applied and allowed to work fully. The procedure is significantly more comfortable than most men expect.

3

Injection

A neuromodulator is injected into penile tissue per the Runels Priapus Toxin® protocol. The injection itself is brief.

4

Done

No downtime. Post-procedure instructions reviewed. You leave and resume your day. Follow-up at 4–6 weeks.

What to Expect

Timeline

Procedure Time

45–60 minutes

Downtime

None

Onset

7–14 days

Duration

3–6 months at 50u · 9–12+ months at 100u

Retreatment

No sooner than 3 months

Often Combined With

P-Shot® (same appointment)

Candidacy

Good fit vs. needs discussion

Likely a good fit

  • Premature ejaculation
  • Vascular erectile dysfunction
  • Peyronie's disease
  • Penile tissue tension
  • No neuromuscular conditions

We'll need to discuss

  • Neuromuscular disease (myasthenia gravis, ALS)
  • Aminoglycoside antibiotic use
  • Botulinum toxin injection within 3 months to any site
  • Active infection at injection site
  • Pregnancy (partner — discuss implications)

Certified Provider — Verify Credentials

Verify Shannon's Priapus Toxin® certification on the official CMA provider directory.

Verify Certification →

Pricing

$1,250 + HST

Added to a P-Shot® or O-Shot® instead? +$1,000 + HST — that rate is available only as an add-on to those procedures.

This is a procedure price, not a per-unit rate. Genital neurotoxin is a different service from facial neurotoxin and is not priced the same way — the two prices are not comparable.

Book this directlyYou can book these online yourself. You do not need the complimentary coordinator appointment or a clinical assessment first, and returning patients do not need a new assessment — Jane collects the medical history and sends the preparation instructions either way.One treatment addresses the factors that treatment targets. Sexual function usually has more than one contributor, which is why we generally prefer a comprehensive program that works on several at once. Booking a single treatment is a perfectly reasonable choice — we just want you to know the difference.

Your symptom is where the conversation starts — not where the assessment ends.

Two people with the same complaint can need very different things. Sexual function is affected by blood flow, tissue health, pelvic-floor function, hormones and metabolic health, medications, sleep, stress and general health — and more than one of those is usually involved.

ProactiveThings work; you want to keep them working.
Early changeSomething shifted and did not shift back.
EstablishedA clear, persistent problem.
ComplexLongstanding, or layered with other health issues.

How much treatment, and in what order, is decided at your clinical assessment — not from a web page or a quiz. Age is part of the context, not the deciding factor. Individual treatments remain available. Read the full picture →

Part of these programs

Transparent by Design

What this costs

Priapus Toxin™
$1,250
With the P-Shot®
$2,500
Both treatments together.

These are our standard investment amounts for Priapus Toxin™.

Whether this treatment is right for you, and how much of it you need, is determined at your clinical assessment — not here, and not before we have met you. See our full pricing page for every standard investment amount.

Two or three years is long enough to wait

Complimentary Sexual Function Program Overview Appointment is confidential, no-pressure, and usually clarifies things fast. Most men leave knowing exactly whether this is the right direction for them.

Book your Complimentary Program Overview Appointment — choose how you would like to meetIn PersonNiagara FallsPhoneFrom anywhereZoomPrivate videoThis conversation is optional. If you already know you are ready for a clinical assessment, book that directly — you do not need this conversation first, and you do not need our approval. Read Patient Reviews

Flexible Payment

Money shouldn't be the reason you wait

We really do work with our patients — money should never be the reason you don't feel amazing. Most programs can be split into manageable monthly payments through Beautifi, our primary healthcare-financing partner. Checking your options is a soft credit check that won't affect your score — no obligation.

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Individual results vary and are not guaranteed. Priapus Toxin® is an off-label application of botulinum toxin type A. All procedures are performed under medical delegation from our Medical Director. Seek emergency care immediately if erection persists beyond 4 hours.
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