Evidence-Based Practice
We never fabricate statistics or cite research we cannot verify. This page links to the actual published studies behind the treatments we offer — so you can read the evidence yourself and ask us informed questions.
Our Commitment to Evidence Honesty
Regenerative medicine is a rapidly evolving field. Some treatments have robust randomized controlled trial evidence. Others have promising pilot study data with larger trials ongoing. We tell you exactly which is which. We do not present pilot data as definitive proof, and we do not present established evidence as uncertain to seem humble. Shannon will give you an accurate picture of what the research supports for your specific situation at your assessment.
Erectile Dysfunction · GAINSwave® · P-Shot™
Sexual Medicine Society of North America · 2024 Annual Meeting
Systematic Review and Meta-Analysis: Low-Intensity Shockwave Therapy for Erectile Dysfunction
A systematic review and meta-analysis presented at SMSNA 2024 found LiSWT to be the most efficacious single regenerative treatment for erectile dysfunction, with statistically significant improvement in validated erectile function scores versus sham control across multiple randomized controlled trials.
This is the most current comprehensive review of the LiSWT evidence base for ED and is the foundation for GAINSwave® program recommendations at Revitalize Your Health.
Journal of Sexual Medicine · University of Virginia · 2024
Long-Term Follow-Up of Randomized Sham-Controlled Trial of LiSWT for Erectile Dysfunction
Long-term follow-up data from a randomized sham-controlled trial at the University of Virginia showed statistically significant improvements in erectile function scores at both one and two years post-treatment — among the strongest long-term evidence of any non-surgical ED intervention currently available.
Two-year durability data distinguishes LiSWT from treatments that show initial response but limited long-term benefit.
Journal of Sexual Medicine · Aristotle University of Thessaloniki · 2021
Intracavernous Injection of Platelet-Rich Plasma for Erectile Dysfunction: A Randomized Double-Blind Placebo-Controlled Clinical Trial
A double-blind, randomized, placebo-controlled trial conducted by eight urologists found PRP injections significantly improved IIEF erectile function scores, with more than two-thirds of men reporting meaningful improvement and zero procedural complications in the treatment group.
This is the highest-quality evidence currently available specifically for PRP (P-Shot® mechanism) in erectile dysfunction.
Search on PubMed →Female Sexual Function · O-Shot® · Clitoxin™ · GAINSwave for Her®
Journal of Women's Health Care · Runels & Runnels · 2024
Pilot Study: Clitoral Injection of IncobotulinumtoxinA (Clitoxin™) for Female Sexual Dysfunction
This pilot study reported that Clitoxin™ alone improved Female Sexual Function Index total scores by an average of 8 points. When combined with O-Shot® PRP in the same appointment, the average FSFI improvement was 12 points — sufficient to move the average woman presenting with sexual dysfunction to the average score reported by women who describe their sex lives as satisfying. For comparison: FDA-approved flibanserin improves FSFI by an average of 5.3 points; bremelanotide by an average of 3.6 points.
This is a pilot study pending larger replication. Shannon will discuss the limitations of this evidence honestly at your assessment.
Obstetrics & Gynecology · 2026
Randomized Controlled Trial: Platelet-Rich Plasma for Female Sexual Function
A randomized controlled trial found PRP injections into vaginal tissue significantly improved female sexual function scores versus control, with no serious adverse events reported in the treatment group.
One of the highest-quality trials specifically examining PRP for female sexual dysfunction to date.
Urinary Incontinence · EMSELLA® · Pelvic Floor
BTL Clinical White Paper · Peer-Reviewed Data
Clinical Outcomes of EMSELLA® HIFEM Protocol for Urinary Incontinence
In a clinical study of patients treated with the standardized 6-session EMSELLA® protocol: 95% reported significant improvement in quality of life; 100% demonstrated improved pelvic floor muscle awareness; 67% eliminated or significantly reduced use of incontinence pads. EMSELLA® is FDA-cleared for urinary incontinence and for improvement of sexual function through pelvic floor strengthening.
These figures are sourced from the BTL published clinical white paper. Shannon attributes statistics to their correct source and does not inflate what the numbers show.
Published Clinical Data · Samuels & Evans
HIFEM Technology for Female Sexual Function Improvement
A peer-reviewed study found improvements in both sexual function scores and urinary incontinence measures following the EMSELLA® protocol in women, supporting the dual-indication clearance for both urinary and sexual function outcomes.
Supports the combined pelvic health and sexual function approach used at Revitalize Your Health.
Peyronie's Disease
American Urological Association Guidelines
AUA Guidelines: Low-Intensity Shockwave Therapy as a Treatment Option for Peyronie's Disease
The American Urological Association recognizes low-intensity shockwave therapy as a treatment option for Peyronie's disease, based on evidence showing reduction in plaque size, improvement in curvature, and reduction in pain-associated symptoms.
Guideline recognition by the AUA distinguishes LiSWT for Peyronie's from purely experimental interventions.
Hair Restoration · Vampire Hair Restoration™
Stem Cells Translational Medicine · Gentile et al. · 2017
A Randomized Blinded Trial of PRP versus Placebo for Androgenic Alopecia
A double-blind, placebo-controlled randomized trial demonstrated statistically significant increases in hair count, hair density, and hair thickness following three PRP treatments versus control, with no serious adverse events. Multiple subsequent systematic reviews have confirmed consistent improvements in androgenic alopecia across patient populations.
This is one of the strongest trials specifically designed for PRP hair restoration, with histological confirmation of follicular changes.
Search on PubMed →Lichen Sclerosus
Journal of Sexual Medicine · Goldstein et al.
PRP Injection for Vulvar Lichen Sclerosus: Clinical Outcomes
Published case series and pilot data reported significant improvement in FSFI scores, symptom severity, and tissue appearance following PRP injection in women with vulvar lichen sclerosus. Histological analysis in some studies confirmed actual tissue regeneration — increased collagen density, improved vascularity, and reduced inflammatory infiltrate — rather than symptom masking.
Larger controlled trials are ongoing. PRP for lichen sclerosus is used at Revitalize Your Health alongside — not replacing — standard topical steroid therapy.
Shannon will walk you through exactly what the research supports — and does not support — for your specific condition at your assessment. No inflation. No uncertainty theater. Just honest clinical interpretation.
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